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What is the Difference Between Delta 8, Delta 9 and CBD

What is the Difference Between Delta 8, Delta 9 and CBD?

By Joe Kryszak Published on 07/13/2021

What are Cannabinoids?

Cannabinoids are a diverse group of naturally occurring compounds inherent to the hemp plant – which is a federally legal class of the cannabis plant (more specifically, the cannabis Sativa plant). Within the collection of more than 400 compounds identified in the industrial hemp plant, approximately 100 are recognized as phytocannabinoids (found within the plant itself).

Delta 9 tetrahydrocannabinol (which we usually call Delta 9 THC) stands out as the most renowned among these compounds. It is popular because it serves as the primary psychoactive component in both hemp and cannabis plants. Another significant portion is Cannabidiol (CBD), combining around 40% of the plant’s resin extract. Delta 8 follows, which is gaining substantial amounts of interest from users and researchers alike.

What are Cannabinoids

Through their interaction with specific receptors located on cell surfaces, the modulatory impact of cannabinoids is achieved. These receptors, known as cannabinoid receptors (CB1 and CB2), are disseminated through various central nervous system regions. In some cases, this mechanism of action is present among other cannabis products.

In 1992, the discovery of anandamide, a naturally occurring substance in the brain binding to CB1, marked the recognition of endocannabinoids.

The effects induced by cannabinoids are dependent on the specific brain area affected. Alterations to memory, cognition, and psychomotor performance can result from the modulation of the limbic system. While influence on the mesolimbic pathway may impact reward, pleasure responses and pain perception can also be subject to modification.

Cannabinoid-enriched products are gaining more and more buyers because of the supposed health advantages they offer, impacting the greater public health.

Exploring Delta 8 THC

Exploring Delta 8 THC

What is it?

Some refer to Delta 8 THC (sometimes called Delta 8 or just D8) as the “nicer younger sibling” of Delta 9 THC. This cannabinoid is also present in the cannabis plant. To obtain Delta 8 THC, manufacturers employ a special chemical synthesis process.

D8 shares a similar chemical structure to Delta 9 because they both have a chain of carbon atoms. Although Delta 8 has a double bond on its eighth carbon atom, Delta 9’s double bond is found on its ninth carbon atom, a structural difference that’s often highlighted in topics like THCA vs Delta 9 to help understand their distinct properties.

Delta 8 THC is reported to provide experiential benefits such as exhilaration, relaxation, and pain relief. Delta 8 does this with fewer side effects than Delta 9 despite being less potent. That last quality of Delta 8 makes it an ideal choice for users who want to avoid THC, which drug tests may detect.

The lack of extensive studies and legal considerations surrounding Delta 8 THC poses challenges in exploring its potential health benefits. One reason for this is that clinical trials and scientific research on Delta 8 THC are limited.

Despite these limitations, some reports suggest that using Delta 8 THC may lead to various health benefits. These could be relaxation, elevation, and relief. One research also points to the possibility that Delta 8 THC products could have milder side effects and a less pronounced impact on users compared to Delta 9 THC.

Pros and Cons of Delta 8 THC

Pros

Psychoactivity with less intensity

Even though Delta 8 THC is closely related to Delta 9 THC, research states that D8 may produce psychoactive effects but with reduced intensity. This is one of the reasons why Delta 8 THC is very appealing to recreational users and to those who are seeking its possible good effects on the body.

Emerging research about Delta 8 indicates that it has an almost identical structure to Delta 9. Despite this slight difference, Delta 8 is capable of partially stimulating CB1 receptors, which are responsible for the hemp plant’s psychoactive quality. So, rather than full-on intense psychoactivity, Delta 8 only elicits milder psychotropic effects.

Stress relief and relaxation

Several scientific studies claim that Delta 8 THC can produce beneficial stress-relieving and relaxing effects. Many users seek Delta 8-infused products because of their mood and emotional regulatory properties related to the subjects in general.

One anecdotal report regarding Delta 8 discovered that Delta 8 significantly enhanced its test subjects’ self-reported feelings of relaxation. This occurred within 20 minutes of use.

How Delta 8 interacts with the brain’s endocannabinoid system explains this benefit. The CB1 receptors in the body have been linked to modulating the brain’s response to stressful situations. Because Delta 8 can bind weakly to CB1 receptors, it retains enough CB1 stimulation to produce stress-reducing and tension-relieving effects without the high associated with marijuana usage.

Healthcare workers, massage therapists, fast-paced kitchen staff, and careers prone to high-pressure situations may derive relaxation from Delta 8 products. The calming effects of Delta 8 have made products like Delta 8 Sleep Gummies increasingly popular among users looking to address stress and promote restful sleep without the intense psychoactive effects of Delta 9.

Appetite stimulation

CB1 receptors are abundant in the human brain, specifically in the hypothalamic and limbic areas of the human brain. Delta 8 THC interacting with CB1 promotes the release of ghrelin, which is a hormone that could stimulate appetite. During this chemical process, Delta 8 also inhibits the release of hormones that signal fullness. Collectively, these biologD8’s processes lead to improved motivation for seeking and consuming food.

People with eating issues will benefit from D8’s ability to arouse appetite. Also, patients under medication, wherein one side effect is suppressed appetite, could profit from this effect of Delta 8.

Pain management

Delta 8 also possesses promising pain-mitigating effects, and this is due to how the cannabinoid modulates specific receptors that are responsible for pain signaling. For this specific benefit, Delta 8 collaborates with CB1 and CB2 receptors.

Laboratory studies tell us that Delta 8 enables increased production of protective biomolecules at pain sites. When Delta 8 “binds to the CB receptors mentioned, it triggers them to release specific molecules. These travel downstream to block or “turn down the volume” on nerve pathways that deliver pain signals to the brain.

Ideal consumers of Delta 8 pain-management skills are those individuals involved in manual labor, repetitive strain, construction workers, servers, mechanics, and those people who are recovering from physical injuries.

Lessened swelling

The human body consists of cytokines. These are proteins released by the immune system, and they function as chemical messengers. Cytokines could be pro or anti-swelling. Delta 8 THC suppresses the generation of cytokines that encourage swelling.

Individuals in sports are prone to experience swelling and soreness, especially if the game is too physical. Because Delta 8 can lessen swelling, products infused with it can be an effective aid for sports enthusiasts.

Increased focus

By considering anecdotal reports from Delta 8 users, we can safely conclude that it can enhance attentional focus without the strong psychoactive effects of Delta 9 THC. Researchers hypothesize that by subtly affecting CB1 receptors, Delta 8 encourages attentiveness among its users.

Though more research is needed, it is believed that Delta 8 interacts with CB1 receptors found in the prefrontal cortex. This brain region is linked to certain execution functions, such as concentration, impulse control, and attention.

People involved in academics, programming, engineering, and other careers demanding increased attention control could utilize Delta 8’s impact on focus.

Cons:

Legal ambiguity

Delta 8 dwells in a legally ambiguous area. This could be a disadvantage to many. The federal government states that hemp-derived products are federally legal as long as they contain less than 0.3% THC. The 2018 Farm Bill is the bill that federally legalized hemp-based products, including Delta 8.

However, certain states have gone to ban Delta 8 sales or possession within their jurisdictions specifically. This conflict could leave a customer uncertain even though Delta 8 is legal at the federal level. It is important to know your state’s laws before buying Delta 8 THC.

Limited research material

As a relatively new cannabinoid, there has been little scientific investigation into Delta 8 for confirmation of its helpful effects and safety. Although there is growing interest in Delta 8 THC, there remain limited clinical trials about it. As compared to better-studied cannabinoids (Delta 9 THC and CBD), we still need substantive research studies discussing the beneficial impacts of Delta 8.

Getting to Know Delta 9 THC

Getting to Know Delta 9 THC

What is it?

Delta 9 THC is one of the main psychoactive compounds that you can extract from a hemp cannabis plant. That is responsible for the production of the characteristic high and intoxicating effects associated with marijuana use.

Understanding the duration of Delta-9 THC in the body is important for users concerned about its effects, detection, and metabolism. Learn more about How Long Does Delta-9 Stay in Your System? by exploring this guide.

When consumed through smoking, vaping, or eating edibles, Delta 9 THC causes its effects by binding to cannabinoid receptors of the body’s endocannabinoid system. This action stimulates the brain’s reward system. The intensity of these effects depends on factors like THC potency and individual tolerance.

When consumed through smoking, vaping, or eating edibles, Delta 9 THC causes its effects by binding to cannabinoid receptors of the body’s endocannabinoid system.

Understanding THC potency plays a significant role in the intensity of Delta 9 THC’s effects. Take a look at our THC Percentage Chart to explore how different levels of THC can influence your experience and help you choose the right product for you.

Delta 9 THC is widely recognized for its psychoactive effects and potential medical benefits, but its legality and usage vary across jurisdictions. If you’re planning to travel, check out this guide on can you fly with delta 9 gummies to better understand potential restrictions or allowances.

As research tells us, Delta 9 THC can provide possible medical benefits. However, potential risks may include temporary issues with impaired coordination or altered perception, similar to medical marijuana plants.

Pros and Cons of Delta 9 THC

Pros

Psychoactive effects

Delta 9 THC’s psychoactive effects are possible because it has a similar shape and chemical behavior to the body’s endocannabinoid neurotransmitters. These are produced within the human central and peripheral nervous systems.

Because of such structure, Delta 9 mimics these chemical signals produced by the human body. Also, Delta 9 strongly binds to specialized cannabinoid receptors situated in the brain, central organs, and immune tissues. Delta 9 excellently activates a subtype of a 9’s receptor that is responsible for memory, cognition, motor control, and pleasure/reward perception.

For many, Delta 9’s psychoactive properties are seen in a negative light. However, people undergoing special care may benefit from Delta 9, especially those who have issues with increasing blood pressure.

Pain Relief

Delta 9 THC demonstrates an evidence-backed effect for reducing pain symptoms due to various conditions. Delta 9’s ability to numb and manage pain is possible because it can activate CB1 9’s CB2 receptors that are embedded in the human endocannabinoid system.

Plenty of individuals will benefit from Delta 9’s capability to encourage pain relief. For instance, weekend warriors and emerging athletes have a high possibility of encountering pain in their careers. Delta 9 products may be able to help them deal with any pain.

Uplifted mood

The dominant cannabinoid can also evoke mood-enhancing effects among its users. Clinical data reveal that Delta 9 binding to CB1 receptors regulates the secretion of vital neurotransmitters such as dopamine and serot9’sn. These two are believed to influence mood and emotional states.

One group of people that could benefit from Delta 9’s mood enhancing outcome will be those who are in high-tension situations. They could be parents overwhelmed by their duties, corporate professionals under work demands, academic people experiencing performance pressures, overworked healthcare professionals, and other related careers.

Sleep aid

Studies suggest Delta 9 increases various sedative signaling molecules in the brain’s nervous system that encourage improved sleep quality. CB1 activation amplifies GABAergic transmission. GABA is the brain’s primary inhibitory neurotransmitter; it opposes stimulatory signals. Delta 9 also elevates melatonin levels, a crucial sleep hormone signaling darkness to induce drowsiness.

Ideal candidates who may benefit include adults and teens who struggle falling or staying asleep nightly for no underlying medical reason identifiable through sleep studies. Frequent flyers, shift workers, professionals in high-responsibility positions, and young parents are also individuals who will likely benefit from Delta 9’s sleep-inducing properties.

Products like Delta 9 Sleep Gummies have been specially formulated to enhance deep sleep and relaxation by leveraging the sedative effects of Delta 9, making them suitable for those experiencing persistent sleep difficulties.

Cons

Short Term Memory Impairment

As you consume Delta 9 THC, it may affect your ability to recall things temporarily. The more Delta 9 you introduce into your system, more likely you are to have difficulty producing new short-term memories. This is one of the adverse effects of Delta 9.

Motor/Cognitive Impairment

Delta 9 could lead to the disruption of cerebellar and frontal cortex signaling. The outcome is impeded coordination and decision-making abilities similar to being wasted from alcohol Stirling’s effects manifest.

Meet CBD

Meet CBD

What does it do?

Having its full name as cannabidiol, CBD is another chemical compound found naturally in a hemp plant. Obtained using a unique extraction process, CBD is gaining popularity because of its perceived health benefits without even being too concerned about ingesting THC (Delta 9). Also, CBD should not show up on a drug test, which is a plus point for many THC product enthusiasts looking to get great benefits from cannabis plants.

Today the market is filled with different types of CBD products, from CBD oils to CBD gummies, which is a clear testimony of the potential CBD brings to online businesses.

Similar to Delta 8 and Delta 9, CBD interacts with human physiology to produce its effects. However, we still need more research to understand how CBD works once inside the human body fully.

Both CBD and Delta 8 indirectly interact with the human endocannabinoid system. Unlike THC, CBD does not directly stimulate the CB1 and CB2 receptors. What it seems to do is increase the levels of anandamide (a natural cannabinoid of the body). By this mechanism of action, CBD offers the human body its purported benefits.

So CBD products enhance what our bodies already do naturally with their own in-built endocannabinoid system. CBD is also legal according to federal law, but it could be treated differently by other states.

Does CBD Contain Delta-9?

CBD products derived from federally legal hemp may contain trace amounts of Delta-9 THC, which is limited to less than 0.3% by law. This minimal presence is insufficient to induce psychoactive effects. Always check the product’s certificate of analysis (COA) to confirm THC levels.

Pros and Cons of CBD

Pros

Natural Pain Relief

Whether ingested or applied topically, CBD enhances the effect of natural cannabinoids on the human body. In turn, the body’s ability to regulate pain is enhanced. By boosting the levels of innate cannabinoids, CBD helps our body ignore or tolerate pain signals.

Athletes and fitness enthusiasts are the first ones to benefit from this effect of CBD. Even elderly individuals who are prone to varying degrees of pain could consider CBD as part of their pain management regimen.

Stress Management

CBD also holds some promising effects for managing stressful situations. The main mechanism behind this effect involves CBD’s influence on serotonin receptors. Serotonin is a special chemical that you may find in the brain.

Disruptions in serotonin signaling contribute to the negative feeling we have when we are facing overwhelming situations in life. CBD is believed to activate special receptors that exert anti-worrying effects and even improve serotonin transmission.

People who are prone to overwhelmed thinking may find microdoses of CBD relieving.

Restorative sleep

This benefit is related to CBD’s ability to manage pain and deal with stress. By reducing factors that can interfere with falling and staying asleep, CBD sets the stage for good old-quality slumber.

People who struggle with sleeplessness are the potential candidates for this CBD benefit. Also, individuals in pain because of an injury could make use of CBD’s power to fall someone into a long-lasting sleep.

Many users report significant improvements in sleep quality when using Pure Dream Sleep Gummies, a CBD-based product designed specifically to help with relaxation and ensuring a restful night’s sleep. This makes it an excellent choice for those struggling with nightly disruptions.

Cons

Adverse effects on the body

CBD products are generally safe if the observed manufacturing process prioritizes the safety of the consumers. However, consuming CBD-infused goods may still lead to certain side effects such as lightheadedness, dry mouth, digestive discomfort, and a sense of fatigue.

Drug Interactions

One caveat of using CBD is that it could interfere with some ongoing medications. For this reason, you should consult a healthcare professional to know your options before incorporating CBD into your routine.

Frequently Asked Questions

About the Author

A leader in the Hemp Industry since 2014, Joe has been at the forefront of the Hemp Industry's innovation and growth. He is passionate about creating an atmosphere of collaboration and education in the Hemp Industry through the growth of Stirling Oils. Prior to this, Joe led strategic growth teams and initiatives at HP, Lenovo, and Amazon. With a degree from SDSU and an MBA from Pepperdine, Joe guided numerous businesses beyond the $1B threshold.